Objection: To evaluate the preoperative neutrophil to lymphocyte ratio in the prognosis of penile cancer. Methods: From the establishment of the database to January 2021, search for the Cochrane Library, PubMed, EMbase, CNKI, Wanfang database, papers that meet the inclusion and exclusion criteria will be obtained for meta analysis using RevMan 5.1 software and STATA 15.0 software. Results: Include 7 studies with 812 patients. The overall survival rate (HR=2.83 95% CI: 1.96-4.08, P<0.001) and progression-free survival rate (HR=1.62 95% CI: 1.17-2.23, P=0.004) of patients with preoperative high NLR was low; the overall survival of patients with positive lymph node metastasis (HR=4.13 95% CI: 2.47-6.90), P<0.001), progression-free survival (HR=3.88 95% CI: 2.15-5.32, P<0.001) is low; lymph node metastasis rate in patients with low NLR (OR=6.99 95%CI: 3.69-13.24, P<0.001) lower. Conclusions: Preoperative high NLR predicts a shorter overall survival rate and progression-free survival rate in patients with penile cancer. It can be considered that NLR is a simple and effective preoperative inflammatory index for predicting the prognosis of patients with penile cancer. It may provide a new perspective and help for clinical work, which will be good news for patients with penile cancer and clinicians.
| Published in | Science Discovery (Volume 9, Issue 6) |
| DOI | 10.11648/j.sd.20210906.12 |
| Page(s) | 283-289 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Penile Cancer, Neutrophil to Lymphocyte Ratio, Prognosis, Meta Analysis
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APA Style
Yang Zeng, Zheng Shuchan, Xie Qun. (2021). The Prognostic Value of Preoperative Neutrophil to Lymphocyte Ratio in the Penile Cancer: Meta Analysis. Science Discovery, 9(6), 283-289. https://doi.org/10.11648/j.sd.20210906.12
ACS Style
Yang Zeng; Zheng Shuchan; Xie Qun. The Prognostic Value of Preoperative Neutrophil to Lymphocyte Ratio in the Penile Cancer: Meta Analysis. Sci. Discov. 2021, 9(6), 283-289. doi: 10.11648/j.sd.20210906.12
AMA Style
Yang Zeng, Zheng Shuchan, Xie Qun. The Prognostic Value of Preoperative Neutrophil to Lymphocyte Ratio in the Penile Cancer: Meta Analysis. Sci Discov. 2021;9(6):283-289. doi: 10.11648/j.sd.20210906.12
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Download@article{10.11648/j.sd.20210906.12,
author = {Yang Zeng and Zheng Shuchan and Xie Qun},
title = {The Prognostic Value of Preoperative Neutrophil to Lymphocyte Ratio in the Penile Cancer: Meta Analysis},
journal = {Science Discovery},
volume = {9},
number = {6},
pages = {283-289},
doi = {10.11648/j.sd.20210906.12},
url = {https://doi.org/10.11648/j.sd.20210906.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20210906.12},
abstract = {Objection: To evaluate the preoperative neutrophil to lymphocyte ratio in the prognosis of penile cancer. Methods: From the establishment of the database to January 2021, search for the Cochrane Library, PubMed, EMbase, CNKI, Wanfang database, papers that meet the inclusion and exclusion criteria will be obtained for meta analysis using RevMan 5.1 software and STATA 15.0 software. Results: Include 7 studies with 812 patients. The overall survival rate (HR=2.83 95% CI: 1.96-4.08, PConclusions: Preoperative high NLR predicts a shorter overall survival rate and progression-free survival rate in patients with penile cancer. It can be considered that NLR is a simple and effective preoperative inflammatory index for predicting the prognosis of patients with penile cancer. It may provide a new perspective and help for clinical work, which will be good news for patients with penile cancer and clinicians.},
year = {2021}
}
TY - JOUR T1 - The Prognostic Value of Preoperative Neutrophil to Lymphocyte Ratio in the Penile Cancer: Meta Analysis AU - Yang Zeng AU - Zheng Shuchan AU - Xie Qun Y1 - 2021/11/12 PY - 2021 N1 - https://doi.org/10.11648/j.sd.20210906.12 DO - 10.11648/j.sd.20210906.12 T2 - Science Discovery JF - Science Discovery JO - Science Discovery SP - 283 EP - 289 PB - Science Publishing Group SN - 2331-0650 UR - https://doi.org/10.11648/j.sd.20210906.12 AB - Objection: To evaluate the preoperative neutrophil to lymphocyte ratio in the prognosis of penile cancer. Methods: From the establishment of the database to January 2021, search for the Cochrane Library, PubMed, EMbase, CNKI, Wanfang database, papers that meet the inclusion and exclusion criteria will be obtained for meta analysis using RevMan 5.1 software and STATA 15.0 software. Results: Include 7 studies with 812 patients. The overall survival rate (HR=2.83 95% CI: 1.96-4.08, PConclusions: Preoperative high NLR predicts a shorter overall survival rate and progression-free survival rate in patients with penile cancer. It can be considered that NLR is a simple and effective preoperative inflammatory index for predicting the prognosis of patients with penile cancer. It may provide a new perspective and help for clinical work, which will be good news for patients with penile cancer and clinicians. VL - 9 IS - 6 ER -
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